Intraperitoneal chemotherapy (IPC) is a cancer treatment technique that involves administering chemotherapy drugs directly into the peritoneal cavity, which is the space between the abdominal organs and the inner lining of the abdomen. This method of chemotherapy is commonly used to treat certain types of cancers that have spread to the peritoneal cavity, such as ovarian cancer and gastrointestinal cancer.
Like any other cancer treatment, IPC may cause side effects. The severity and type of side effects experienced by a patient may depend on various factors, including the type of chemotherapy drugs used, the patient’s overall health, and the duration of treatment. In this article, we will discuss the common side effects associated with IPC.
Nausea and vomiting: Nausea and vomiting are common side effects of chemotherapy, including IPC. Patients may experience mild to severe nausea and vomiting, which may be managed with antiemetic medications.
Fatigue: Fatigue is another common side effect of IPC. Patients may experience tiredness, weakness, and lack of energy. This may be due to the chemotherapy drugs affecting the body’s ability to produce energy.
Abdominal pain: Abdominal pain is a common side effect of IPC. Patients may experience mild to severe pain in the abdomen, which may be managed with pain medications.
Diarrhea: Diarrhea is another common side effect of IPC. Patients may experience loose stools, which may be managed with anti-diarrhea medications.
Constipation: Constipation is a less common side effect of IPC. Patients may experience difficulty passing stools, which may be managed with laxatives.
Hair loss: Hair loss or thinning is a common side effect of chemotherapy, including IPC. Patients may experience hair loss or thinning on the scalp, as well as other parts of the body.
Infection: Chemotherapy drugs can weaken the immune system, making patients more susceptible to infections. Patients may be given antibiotics to prevent or treat infections.
Blood disorders: Chemotherapy drugs can affect the production of blood cells, leading to anemia, thrombocytopenia, and leukopenia. These conditions may require further treatment, such as blood transfusions or growth factors.
Kidney damage: Some chemotherapy drugs used in IPC may cause damage to the kidneys. Patients may need to have their kidney function monitored during treatment.
Hearing loss: Some chemotherapy drugs used in IPC may cause hearing loss. Patients may need to have their hearing monitored during treatment.
Peripheral neuropathy: Some chemotherapy drugs used in IPC may cause nerve damage, leading to symptoms such as numbness, tingling, and weakness in the hands and feet.
Allergic reactions: Some patients may have an allergic reaction to the chemotherapy drugs used in IPC. Symptoms may include hives, itching, and difficulty breathing.
It is important to note that not all patients will experience all of these side effects. The severity and type of side effects experienced by a patient may vary depending on various factors, including the type of chemotherapy drugs used, the patient’s overall health, and the duration of treatment. Patients should discuss any concerns or questions regarding IPC and its potential side effects with their healthcare provider.
